Ophthalmic oil-in-water emulsions containing prostaglandins

Details Ophthalmic oil-in-water emulsions containing prostaglandins Ophthalmic oil-in-water emulsions containing prostaglandins

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 31/557 (2006.01) A61K 47/10 (2006.01) A61K 47/26 (2006.01) A61K 47/44 (2006.01)

Patent

CA 2683672

The present invention refers to an oil-in-water emulsion for ophthalmic application comprising at least one prostaglandin as active agent and a surfactant component comprising a combination of at least two non-ionic surfactants. The emulsion is suitable for medical applications, particularly for the treatment of glaucoma, and has an increased chemical stability of the prostaglandin active agent so to allow long-term storage also at room temperature.

La présente invention porte sur une émulsion huile dans l'eau pour application ophtalmique. Ladite émulsion comprend au moins une prostaglandine comme agent actif et un composant tensio-actif comprenant une combinaison d'au moins deux tensio-actifs non ioniques. L'émulsion est appropriée pour des applications médicales, en particulier pour le traitement du glaucome, et présente une stabilité chimique accrue de l'agent actif prostaglandine de façon à permettre un stockage de longue durée même à température ambiante.

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