Ophthalmic oil-in-water type emulsion with stable positive...

A - Human Necessities – 61 – K

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A61K 9/00 (2006.01) A61K 9/107 (2006.01)

Patent

CA 2586074

An ophthalmic oil-in-water type emulsion, which comprises colloid particles having an oily core surrounded by an interfacial film, said emulsion comprising at least one cationic agent, at least one non ionic surfactant said emulsion having a positive zeta potential and meeting zeta potential stability Test A requirements. Process for making said emulsions. Delivery device selected from the group comprising lenses, ocular patch, implant, insert, said device containing an emulsion according to the invention.

L'invention concerne une émulsion ophtalmique du type huile dans eau comprenant des particules colloïdes renfermant un noyau huileux entouré d'un film interfacial, l'émulsion comprenant au moins un agent cationique, au moins un tensioactif non ionique et possédant un potentiel zêta positif et répondant aux exigences du test A de stabilité du potentiel zêta. L'invention concerne également un procédé de fabrication des émulsions et un dispositif d'administration, sélectionné dans le groupe renfermant des lentilles, un patch oculaire, un implant, un ocusert, renfermant une émulsion selon l'invention.

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