Ophthalmic solution based on diclofenac and tobramycine and...

Details Ophthalmic solution based on diclofenac and tobramycine and... Ophthalmic solution based on diclofenac and tobramycine and...

A - Human Necessities

61

K

A61K 9/08 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2167383

The ophthalmic solution comprises (a) the equivalent to 0.001-0.14 % of Diclofenac itself or an isomer, or a derivative or one of the pharmaceutically acceptable salts thereof; (b) the equivalent to a value of 0.001-0.45 % of Tobramycine, obtained from Tobramycine itself or from an isomer or a derivative or one of its pharmaceutically acceptable salts thereof; (c) optionally a solubilizer, an isotonizer, a pH damper, a viscosizer, a chelator, a preserving agent, and/or an excipient for pharmaceutical hydrogels. Application to the treatment of ocular and otic inflammations and/or infections.

La solution ophtalmique comprend (a) l'équivalent d'une valeur de 0,001-0,14 % de diclofénac, provenant de diclofénac lui-même ou d'un isomère, ou un dérivé ou un de ses sels pharmaceutiquement acceptables; (b) l'équivalent d'une valeur de 0,001-0,45 % de tobramicine, provenant de tobramicine elle-même ou d'un isomère ou un dérivé ou un sel pharmaceutiquement acceptable de celle-ci; (c) éventuellement un agent solubilisant, un agent isotonique, un agent d'atténuation du pH, un agent d'augmentation de la viscosité, un agent dilateur, un conservateur, et/ou un excipient pour des hydrogels pharmaceutiques. Application au traitement d'inflammations et/ou d'infections oculaires et otiques.

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