Ophthalmologic irrigation solutions and method

A - Human Necessities – 61 – K

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A61K 38/00 (2006.01) A61K 31/19 (2006.01) A61K 31/56 (2006.01)

Patent

CA 2493581

Solutions for perioperative intraocular application by continuous irrigation during ophthalmologic procedures are provided. These solutions include multiple agents that act to inhibit inflammation, inhibit pain, effect mydriasis (dilation of the pupil), and/or decrease intraocular pressure, wherein the multiple agents are selected to target multiple molecular targets to achieve multiple differing physiologic functions, and are included in dilute concentrations in a balanced salt solution carrier.

L'invention concerne des solutions destinées à être administrées par voie intraoculaire en période périopératoire par irrigation continue lors de procédures ophtalmologiques. Ces solutions contiennent des agents multiples dont l'action inhibe l'apparition d'une inflammation, inhibe la douleur, engendre une mydriase (dilatation pupillaire) et/ou réduit la pression intraoculaire. Lesdits agents multiples sont sélectionnés pour viser des cibles moléculaires multiples et assurent de ce fait de multiples fonctions physiologiques différentes. Ces agents sont contenus à des concentrations diluées dans un excipient sous forme de solution saline équilibrée.

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