Opiate antagonist implant and process of preparation therefor

A - Human Necessities – 61 – F

Patent

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Details

A61F 2/02 (2006.01) A61K 9/00 (2006.01) A61K 31/439 (2006.01) A61K 31/485 (2006.01) A61K 31/573 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2278137

The present invention provides an opiate antagonist implant which is an admixture of an opiate antagonist, in either acid or base form, and a pharmaceutically acceptable carrier. The admixture is uniformly compressed into a subcutaneously implantable pellet which is effective to release levels of the opiate antagonist over desired amounts of time when subcutaneously implanted in a patient to effectively inhibit the effects of a number of addictive drugs.

La présente invention se rapporte à un implant antagoniste des opiacés qui est un mélange d'un antagoniste d'opiacés, soit sous forme basique ou sous forme acide, et d'un excipient pharmaceutiquement acceptable. Ledit mélange est uniformément comprimé en une pastille susceptible d'être implantée par voie sous-cutanée, qui sert à libérer des concentrations de l'antagoniste d'opiacés, pendant des périodes désirées, après qu'on l'ait implantée chez un patient dans le but d'inhiber efficacement les effets de certaines drogues engendrant une dépendance.

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