Opioid receptor antagonists

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 409/12 (2006.01) A61K 31/335 (2006.01) C07D 307/91 (2006.01) C07D 405/12 (2006.01) C07D 491/04 (2006.01)

Patent

CA 2558652

A compound of the formula (I) (I) wherein the variables X1 to X6, Ra, Rb, R1 to R7 including R3', E, p, j, y, z, A, B and C are as described or a pharmaceutically acceptable salt, solvate, enantiomer, racemate, diastereomer or mixtures thereof, useful for the treatment, prevention or amelioration of obesity and Related Diseases is disclosed.

L'invention concerne un composé de formule (I) (I), dans laquelle les variables X¿1? à X¿6?, R?a¿, R?b¿, R?1¿ à R?7¿ y compris R?3'¿, E, p, j, y, z, A, B et C sont telles que décrites ou un sel, un solvate, un énantiomère, un racémate, un diastéréomère ou des mélanges de ces substances pharmaceutiquement acceptables. Ce composé sert au traitement, à la prévention ou à l'amélioration de l'obésité et de troubles y étant associés.

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