Opiorphin for use as a psychostimulant agent

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/08 (2006.01) A61K 38/55 (2006.01) A61P 25/00 (2006.01) A61P 25/26 (2006.01)

Patent

CA 2725243

The present invention relates to peptides derived from hu-man Basic Proline-rich Lacrimal Pro-tein (BPLP), notably opiorphin, for use as psycho stimulants. These pep-tides are useful in the treatment or prevention of diseases such as obses-sive-compulsive disorder (OCD), nar-colepsy, hypersomnia, vigilance drop, attention-deficit/hyperactivity disor-der (ADHD), attention deficit and/or hyperactivity in adults and in chil-dren, depression, bipolar disease, dysthymic disorder and cyclothymic disorder.

La présente invention concerne des peptides dérivés de la protéine lacrymale riche en proline (BPLP) humaine, notamment lopiorphine, destinés à être utilisés en tant que psychostimulants. Ces peptides sont utiles dans le traitement ou la prévention de maladies telles quun trouble obsessionnel compulsif (TOC), la narcolepsie, lhypersomnie, les baisses de vigilance, un trouble déficitaire de l'attention avec hyperactivité (ADHD), un trouble déficitaire de lattention et/ou lhyperactivité chez les adultes et les enfants, la dépression, un trouble bipolaire, un trouble dysthymique et un trouble cyclothymique.

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