Optic nerve protecting agents containing .alpha.1 receptor...

Details Optic nerve protecting agents containing .alpha.1 receptor... Optic nerve protecting agents containing .alpha.1 receptor...

A - Human Necessities

61

K

A61K 31/517 (2006.01) A61K 31/495 (2006.01) A61K 31/496 (2006.01) A61P 27/02 (2006.01) A61P 27/06 (2006.01)

Patent

CA 2454544

A novel pharmacological effect of an .alpha.1 receptor blocker is found out. As the results of studies on the novel pharmacological effect of the .alpha.1 receptor blocker, it is clarified that this blocker has an effect of protecting optic nerve. Thus, the .alpha.1 receptor blocker is expected as being useful in optic nerve protecting agents to be used in treating retinal diseases typified by normotensive glaucoma, retinal vein occlusion, diabetic retinopathy, ischemic optic neuropathy, macular degeneration, retinitis pigmentosa and Leber~s disease.

L'invention concerne un nouvel effet pharmacologique d'un bloqueur de récepteur .alpha.¿1?. Les recherches portant sur le nouvel effet pharmacologique d'un bloqueur de récepteur .alpha.¿1 ?ont permis d'établir que ce bloqueur a un effet protecteur sur le nerf optique. De ce fait, on s'attend à ce que le bloqueur de récepteur .alpha.¿1? soit utile dans les agents protecteurs de nerf optique utilisés dans le traitement des maladies de la rétine, du type de glaucome normotensif, l'occlusion veineuse rétinienne, la rétinopathie diabétique, la neuropathie optique ischémique, la dégénérescence maculaire, retinititis pigmentosa et la maladie de Leber.

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