G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 21/75 (2006.01) C09K 19/00 (2006.01) G01N 37/00 (2006.01) G02F 1/1337 (2006.01)
Patent
CA 2334238
Interactions between molecules which are components of self-assembled monolayers and other molecules can be amplified and transduced into an optical signal through the use of a mesogenic layer. The invention provides a device and methods for detecting analytes. The device comprises a substrate onto which a self-assembled monolayer is attached and a mesogenic layer which is anchored by the self-assembled monolayer. The mesogenic layer undergoes a change in conformation in response to the molecular interaction.
Des interactions entre molécules qui sont des composantes de couches simples à autoassemblage et d'autres molécules peuvent être amplifiées et converties en un signal optique par l'utilisation d'une couche mésogène. La présente invention concerne un dispositif et des procédés permettant de détecter des substances à analyser. Ce dispositif comprend un substrat sur lequel est fixée une couche simple à autoassemblage et une couche mésogène ancrée par la couche simple à autoassemblage. La couche mésogène change de conformation en réponse à l'interaction moléculaire.
Abbott Nicholas L.
Dubrovsky Timothy B.
Gupta Vinay K.
Shah Rahul
Skaife Justin J.
Smart & Biggar
The Regents Of The University Of California
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