Optical determination of glucose utilizing boronic acid...

C - Chemistry – Metallurgy – 07 – F

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C07F 5/02 (2006.01) A61K 49/00 (2006.01) C07C 309/71 (2006.01) C07D 213/82 (2006.01) G01N 33/52 (2006.01) G01N 33/66 (2006.01)

Patent

CA 2630790

Embodiments of this invention relate to an improved optical method and/or sensor for measuring the concentration of polyhydroxy substituted organic molecules in aqueous or organic media. In one application, the method and sensor monitor the concentration of sugars, i.e., glucose or fructose, in aqueous solution in vitro. In particular, the method and sensor are adapted to monitor the concentration of sugars, i.e., glucose or fructose, in blood while implanted intravascularly.

L'invention concerne un procédé et/ou un capteur optiques, améliorés, de mesure de la concentration de molécules organiques polyhydroxy-substituées dans des milieux aqueux ou organiques. Dans un mode de réalisation, le procédé et le capteur servent à contrôler la concentration de sucres, c.-à-d. de glucose ou de fructose, dans une solution aqueuse in vitro. Le procédé et le capteur selon l'invention sont particulièrement destinés à contrôler la concentration de sucres, c.-à-d. de glucose ou de fructose, dans le sang, ledit capteur étant implanté de façon intravasculaire.

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