A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 49/00 (2006.01) C09B 23/08 (2006.01)
Patent
CA 2686089
The present invention relates to imaging agents suitable for in vivo optical imaging, which comprise conjugates of pentamethine cyanine dyes having reduced non-specific binding, eg. to plasma proteins. This is achieved by control of the nature and location of the sulfonic acid substituents, in particular the sulfoalkyl groups. Also disclosed are pharmaceutical compositions and kits, as well as in vivo imaging methods.
La présente invention se rapporte à des agents de formation d'image convenant à la formation d'images optiques in vivo, qui comprennent des conjugués de colorants de cyanine pentaméthine présentant des liaisons non spécifiques réduites, par exemple à des protéines de plasma. Ceci est obtenu par la régulation de la nature et de l'emplacement de substituants à l'acide sulfonique, en particulier les groupements sulfo alkyle. Sont également concernées des compositions pharmaceutiques et des trousses, de même que des procédés de formation d'images in vivo.
Cooper Michael Edward
Cuthbertson Alan
Johannesen Edvin Wilhelm
Fetherstonhaugh & Co.
Ge Healthcare As
LandOfFree
Optical imaging agents does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Optical imaging agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Optical imaging agents will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1857383