Optical polymer mixtures for gastric retentive tablets

Details Optical polymer mixtures for gastric retentive tablets Optical polymer mixtures for gastric retentive tablets

A - Human Necessities

61

K

A61K 9/22 (2006.01) A61K 47/34 (2006.01) A61K 47/38 (2006.01) A61K 31/155 (2006.01) A61K 31/195 (2006.01) A61K 31/496 (2006.01)

Patent

CA 2409999

Unit dosage form tablets for the delivery of pharmaceuticals are formed of the pharmaceutical dispersed in a solid unitary matrix that is formed of a combination of poly(ethylene oxide) and hydroxypropyl methylcellulose. The combination offers unique benefits in terms of release rate control and reproducibility while allowing both swelling of the tablet to effect gastric retention and gradual disintegration of the tablet to clear the tablet from the gastrointestinal tract after release of the drug has occurred.

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