Optical system for cell imaging

Details Optical system for cell imaging Optical system for cell imaging

G - Physics

02

B

G02B 27/09 (2006.01) B01L 3/00 (2006.01) B01L 9/06 (2006.01) G01N 15/04 (2006.01) G01N 33/50 (2006.01) G02B 21/08 (2006.01)

Patent

CA 2588126

A microscope system (10, 10~, 10~~, 10~~~)includes a laser (18) or light emitting diode (18~~~) that generates source light having a non-uniform spatial distribution. An optical system includes an objective (40) defining a field of view, and an optical train (22, 22~, 22~~, 22~~~) configured to convert the source light into an enlarged-diameter collimated light, to spatially homogenize the enlarged-diameter collimated light, and to couple the homogenized enlarged-diameter collimated light into the objective to provide substantially uniform static illumination of the field of view. A camera system (56) is statically optically coupled by the objective with at least most of the field of view.

L'invention concerne un système de microscopie (10, 10', 10'', 10''') équipé d'un laser (18) ou d'une diode électroluminescente (18") qui génère une lumière source présentant une distribution spatiale non uniforme. Un système optique comprend un objectif délimitant un angle de champ, et un trajet optique (22, 22', 22'', 22''') configuré pour convertir la lumière source en une lumière collimatée de diamètre agrandi, de façon à homogénéiser cette dernière, et pour coupler la lumière collimatée de diamètre agrandi homogénéisée à l'intérieur de l'objectif afin de produire une illumination statique sensiblement uniforme de l'angle de champ. Un système de caméra (56) est couplé de façon optiquement statique par l'objectif avec au moins la majeure partie de l'angle de champ.

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