Optically active aminopyridine derivative and use thereof

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 213/75 (2006.01) A61K 31/44 (2006.01) C07D 213/89 (2006.01) C07D 401/04 (2006.01)

Patent

CA 2110729

ABSTRACT OF THE DISCLOSURE A (+) antipode of an aminopyridine derivative, which is represented by the formula (I) Image (I) wherein eacy symbol is as defined in the Specification, a salt thereof, and the use thereof as an agent for circulatory diseases. The compound of the invention is extremely low toxic and shows strong and long-lasting pharmacological action such as vasodepressor action. When used as a preventive or therapeutic agent for hypertension, in particular, the compound affords stable antihypertensive action even at diminished administration frequencies. Also, it can be used as a lipometabolism-improving agent.

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