C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/223, 260/266
C07D 455/04 (2006.01) A61K 31/495 (2006.01) C07C 229/18 (2006.01) C07D 215/233 (2006.01)
Patent
CA 1326026
Abstract: Optically Active Benzoquinolizine Compounds, Process for preparing Same, and Antibacterial Preparation Containing same as Active Ingredient An optically active (+)-isomer of a benzoquinolizine compound of the formula [I], is provided: Image [I] where X1 represents a halogen atom, and R1 and R2 represent lower alkyl groups, a physiologically acceptable salt thereof, or a hydrate or either of the foregoing compounds. The compounds [I] - (+) exhibit an excellent antibacterial activity. Also, the compounds exhibit high solubility in water. Therefore, the compounds of the present invention are usable for the treatment of infectious diseases and usable in aqueous liquid preparations such as injections.
586275
Nagamatsu Yasuhiro
Suzuki Senji
Tomari Masazumi
Gowling Lafleur Henderson Llp
Tokyo Tanabe Company Limited
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