Optically active .beta.-lactams and method of their production

C - Chemistry – Metallurgy – 07 – D

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C07D 205/08 (2006.01) C07D 205/085 (2006.01) C07D 403/04 (2006.01) C07D 413/04 (2006.01) C07F 7/10 (2006.01) C07F 7/18 (2006.01)

Patent

CA 1250287

ABSTRACT OF THE DISCLOSURE Optically active .beta.-lactams of the general formula Image wherein R1 is an amino or protected amino group, R2 is an organic residue bonding through a carbon atom thereof and R3 is the residue remaining after removal of the .alpha.-amino group from an optically active .alpha.-amino acid or a derivative thereof as well as a method of producing the same. These .beta.-lactams are useful, for example, as an intermediate in the synthesis of a variety of antibiotics such as monocyclic .beta.-lactams.

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