Optically-active di[3-chloro-2-oxy-...

Details Optically-active di[3-chloro-2-oxy-... Optically-active di[3-chloro-2-oxy-...

C - Chemistry, Metallurgy

07

C

260/562, 260/594

C07C 59/255 (2006.01)

Patent

CA 1238923

ABSTRACT OF THE DISCLOSURE A process is disclosed for the production of a novel optically-active di-[3-chloro-2-oxy-propyltrimethyl- ammonium]-tartrate of the formula: Image The process involves converting racemic 3-chloro-2-oxy- propyltrimethylammonium chloride by racemate resolution with optically-active tartaric acid into the optically- active di-[3-chloro-2-oxy-propyltrimethylammonium]-tartrate. Such optically-active tartrate compound is dissociated in tartaric acid and optically-active 3-chloro-2-oxy- propyltrimethylammonium chloride and the latter is converted with inorganic cyanides. From the product, the production of optically-active carnitine nitrile chloride can be achieved.

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