A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/715 (2006.01) A01N 43/04 (2006.01) A01N 59/16 (2006.01) A61K 9/00 (2006.01) A61K 33/24 (2006.01) A61K 39/395 (2006.01) A61K 39/40 (2006.01) A61K 39/42 (2006.01) A61K 39/44 (2006.01) A61K 41/00 (2006.01) A61K 49/00 (2006.01) A61K 51/00 (2006.01) A61M 36/14 (2006.01) G01N 24/00 (2006.01) A61K 9/51 (2006.01)
Patent
CA 2399293
This invention is generally in the field of improved methods for the localized delivery of heat and the localized imaging of biological materials. The delivery may be in vitro or in vivo and is useful for the localized treatment of cancer, inflammation or to other disorders involving overproliferation of tissue. The method is also useful for diagnostic imaging. The method involves localized induction of hyperthermia in a cell or tissue by delivering nanoparticles to said cell or tissue and exposing the nanoparticles to an excitation source under conditions wherein they emit heat.
La présente invention concerne globalement le domaine des procédés améliorés d'apport localisé de chaleur et d'imagerie localisée de matières biologiques. L'apport peut être effectué in vitro ou in vivo et trouve son utilité pour traiter de manière localisée le cancer, les inflammations ou d'autres pathologies impliquant la prolifération excessive de tissus. Le procédé est également utile pour l'imagerie de diagnostic. Le procédé implique l'induction localisée d'une hyperthermie dans une cellule ou un tissu au moyen de l'apport de nanoparticules à ladite cellule ou audit tissu suivi de l'exposition des nanoparticules à une source d'excitation dans des conditions où elles émettent de la chaleur.
Halas Nancy J.
Hirsch Leon R.
West Jennifer L.
Borden Ladner Gervais Llp
Rice University
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