Optically active phenethanolamines and method for increasing...

C - Chemistry – Metallurgy – 07 – C

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C07C 229/38 (2006.01) C07C 51/367 (2006.01) C07C 51/487 (2006.01) C07C 65/32 (2006.01) C07C 243/38 (2006.01) C07D 291/04 (2006.01)

Patent

CA 1145766

ABSTRACT Compounds of the formula (I): Image wherein: R1 is hydrogen or flourine; R2 is hydrogen or hydroxy; R3 is hydrogen, hydroxy, fluorino, amino- carbonyl, methylaminocarbonyl, methoxycarbonyl or acetoxy; ? and ? both are asymmetric carban atoms having the R absolute stereochemical configuration; with the limitation that at least one of R1 and R2 is hydrogen; or pharmaceutically acceptable salts thereof are extremely potent inotropic agents.

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