Optically active triazole derivatives and compositions

Details Optically active triazole derivatives and compositions Optically active triazole derivatives and compositions

C - Chemistry, Metallurgy

07

D

C07D 403/10 (2006.01) A61K 31/41 (2006.01) C07D 249/08 (2006.01) C07D 301/19 (2006.01) C07D 303/14 (2006.01) C07D 303/16 (2006.01) C07D 303/40 (2006.01) C07D 405/06 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2049799

A B S T R A C T The compound (+)-2-(2,4-difluorophenyl)-1-[3-[(E)-4- (2,2,3,3-tetrafluoropropoxy)styryl]-1H-1,2,4-triazol-1-yl]-3-(1H- 1,2,4-triazol-1-yl)propan-2-ol, which has antifungal activity, and is valuable in treatment of fungal infections in man and in other animals, pharmacologically acceptable salts thereof, solvates thereof and solvates of salts thereof, and also methods for its preparation, and medicinal compositions characterised in that they contain it as active ingredient. The invention also concerns intermediates for the preparation of the compound shown by the formula ((+)-I) and also methods for their preparation.

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