Optically pure salts of pyridinylmethyl...

Details Optically pure salts of pyridinylmethyl... Optically pure salts of pyridinylmethyl...

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/4439 (2006.01) A61P 1/04 (2006.01)

Patent

CA 2337581

The novel optically pure compounds Na+, Mg2+, Li+, K+, Ca2+ and N+(R)4 salts of (+)-5-methoxy-2-[[(4-methoxy-3,5- dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole, where R is an alkyl with 1-4 carbon atoms, processes for the preparation thereof and pharmaceutical preparations containing the compounds as active ingredients, as well as the use of the compounds in pharmaceutical preparations and intermediates obtained by preparing the compounds. The novel compounds are represented by: Image Ia (+)-enantiomer wherein n is 1 or 2 and X is Na+, Mg2+, Li+, K+, Ca2+ or N+(R)4.

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