Optimal polyvalent vaccine for cancer

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/00 (2006.01) A61P 35/00 (2006.01) C12Q 1/02 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2521812

This invention also provides a method for identification of the optimal combination of a polyvalent vaccine against a cancer comprising steps of: a) selection of an appropriate cancer cell line; and b) detection of the expression of antigens on the surface of said cell line of the cancer, wherein the antigens expressed will be used in the polyvalent vaccine. This invention also provides a method for identification of the optimal combination of a polyvalent vaccine against a cancer comprising steps of: a) selection of an appropriate cancer cell line and b) detection of the immunogenicity will be used in the polyvalent vaccine. This invention provides various uses of the identified polyvalent vaccine.

La présente invention a trait à un procédé d'identification de la combinaison optimale d'un vaccin polyvalent contre un cancer comprenant les étapes suivantes : a) la sélection d'une lignée de cellules cancéreuses appropriée ; et b) la détection de l'expression d'antigènes à la surface de ladite lignée cellulaire du cancer, dans laquelle les antigènes exprimés seront utilisés dans le vaccin polyvalent. L'invention a également trait à un procédé pour l'identification de la combinaison optimale d'un vaccin polyvalent contre un cancer comprenant les étapes suivantes : a) la sélection d'une lignée de cellules cancéreuses appropriée ; et b) la détection de l'antigénicité qui sera utilisée dans le vaccin polyvalent. L'invention a trait en outre à diverses utilisations du vaccin polyvalent identifié.

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