Optimal polyvalent vaccine for cancer

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/00 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2624559

This invention provides a method for identification of the optimal combination of a polyvalent vaccine against a cancer comprising steps of : a) selection of an appropriate cancer cell line; and b) detection of the expression of antigens on the surface of said cell line of the cancer, wherein the antigens expressed will be used in the polyvalent vaccine. This invention also provides a method for identification of the optimal combination of a polyvalent vaccine against a cancer comprising steps of : a) selection of an appropriate cancer cell line and b) detection of the immunogenicity will be used in the polyvalent vaccine. This invention provides various uses of the identified polyvalent vaccine.

La présente invention concerne un procédé d'identification de la combinaison optimale d'un vaccin polyvalent contre un cancer qui se déroule de la manière suivante: (a) on sélectionne une lignée cellulaire cancéreuse appropriée et (b) on détecte l'expression des antigènes sur la surface de ladite lignée cellulaire du cancer, lesdits antigènes exprimés étant ensuite utilisés dans le vaccin polyvalent. Cette invention porte également sur un procédé d'identification de la combinaison optimale d'un vaccin polyvalent contre un cancer qui comprend les étapes suivantes: (a) la sélection d'une lignée cellulaire cancéreuse appropriée et (b) la détection de l'immunogénicité qui sera utilisée dans le vaccin polyvalent. Cette invention porte également sur diverses utilisations du vaccin polyvalent identifié.

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