Optimally expanded, collagen sealed eptfe graft with...

A - Human Necessities – 61 – L

Patent

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Details

A61L 27/48 (2006.01) A61F 2/06 (2006.01)

Patent

CA 2593983

The present invention provides a method of making a temporarily blood-tight implantable ePTFE material for improved tissue ingrowth and delivery of therapeutic agents comprising providing an ePTFE material having an average internodal distance of 60 - 200 microns, preparing a biodegradable hydrogel sealant also comprising a therapeutic agent infusing the ePTFE material with the biodegradable hydrogel sealant, and curing the ePTEE material.

La présente invention concerne une méthode de fabrication d'un matériau ePTFE implantable temporairement étanche au sang pour l'interposition tissulaire améliorée et l'administration d'agents thérapeutiques, consistant à utiliser un matériau ePTFE présentant une distance internodale moyenne comprise entre 60 et 200 microns, à préparer un matériau d'étanchéité à base d'hydrogel biodégradable comprenant également un agent thérapeutique, à imprégner le matériau ePTFE à l'aide du matériau d'étanchéité d'hydrogel biodégradable, et à durcir le matériau ePTFE.

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