Optimised micro-organism strains for nadph-consuming...

C - Chemistry – Metallurgy – 12 – N

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C12N 9/02 (2006.01) C12P 7/00 (2006.01) C12P 13/00 (2006.01) C12P 33/00 (2006.01)

Patent

CA 2544507

The invention relates to optimised micro-organism strains for the biotransformation production of molecules having NADPH-consuming biosynthetic pathways. The inventive strains can be used in NADPH-consuming biotransformation methods. Said strains are characterised in that one or more NADPH-oxidising activities are limited.

La présente invention concerne des souches de microorganismes optimisées pour la production par biotransformation, de molécules ayant des voies de biosynthèse consommatrices de NADPH. Les souches selon l~invention sont utilisables dans des procédés de biotransformation consommateurs de NADPH. Elles sont caractérisées par en ce qu~elle comprennent la limitation d~une ou plusieurs activité(s) oxydant le NADPH.

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