C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A61K 31/70 (2006.01) C07H 21/00 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2319086
The invention provides optimized antisense oligonucleotides complementary to the DNA methyltransferase gene or its RNA transcript. The invention further provides methods for using such antisense oligonucleotides as analytical and diagnostic tools, as potentiators of transgenic plant and animal studies and gene therapy approaches, and as potential therapeutic agents.
L'invention porte sur des oligonucléotides antisens optimisés complémentaires au gène codant l'ADN méthyltransférase ou son produit de transcription en ARN. L'invention porte également sur des procédés d'utilisation de ces oligonucléotides antisens utilisés comme outils d'analyse et de diagnostic, comme agents de potentialisation d'études sur les plantes transgéniques et les animaux, et dans les recherches en thérapie génique, et comme agents thérapeutiques potentiels.
Methylgene Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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