Optimized dosing for drug coated stents

Details Optimized dosing for drug coated stents Optimized dosing for drug coated stents

A - Human Necessities

61

L

A61L 31/16 (2006.01)

Patent

CA 2458828

The inventors have found that both the drug dose and drug release profiles are significant factors for the safety and efficacy of drug coated stents. The inventors have identified optimum dosing and release kinetics for drug coated stents. In particular, the inventors have determined dosing and release kinetics that permit the delivery of the lowest effective drug dosage, thus enhancing patient safety and minimizing any side effects from the drug.

L'invention concerne des profils de dosage de médicaments et de libération de médicaments, se révélant être d'importants facteurs dans la sécurité et l'efficacité d'extenseurs enduits d'un médicament. L'invention a permis d'identifier un dosage optimal et une cinétique de libération pour les extenseurs enduits de médicaments. L'invention permet, en particulier, de déterminer un dosage et une cinétique de libération permettant d'administrer le plus faible dosage de médicament efficace, améliorant ainsi la sécurité du patient et minimisant les effets secondaires du médicament.

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