A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/285 (2006.01) C07K 14/07 (2006.01) C12N 15/863 (2006.01)
Patent
CA 2751301
The present invention relates to a replication deficient recombinant virus encoding at least one antigen and/or antigenic epitope, wherein expression of said antigen and/or antigenic epitope is regulated by a transcriptional control element comprising at least two elements driving early expression of said antigen and/or antigenic epitope and the use of said replication deficient recombinant virus as medicament or vaccine.
La présente invention concerne un virus recombinant à réplication déficiente codant au moins pour un antigène et/ou un épitope antigénique, l'expression dudit antigène et/ou dudit épitope antigénique étant régulée par un élément de commande transcriptionnel qui comporte au moins deux éléments entraînant l'expression précoce dudit antigène et/ou épitope antigénique. L'invention concerne également l'utilisation dudit virus recombinant à réplication déficiente en tant que médicament ou vaccin.
Baur Karen
Brinkmann Kay
Hausmann Juergen
Bavarian Nordic A/s
Goudreau Gage Dubuc
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