Optimized fc variants

Details Optimized fc variants Optimized fc variants

C - Chemistry, Metallurgy

07

K

C07K 16/00 (2006.01) C07K 16/28 (2006.01) C12N 15/13 (2006.01)

Patent

CA 2755905

The invention relates to a variant of a parent polypeptide comprising an Fc region, which variant exhibits increased binding to FcRn as compared to said parent polypeptide and comprises at least one amino acid modification in the Fc region.

La présente invention concerne un variant d'un polypeptide parent comprenant une région Fc, ledit variant présentant une liaison augmentée à FcRn par rapport audit polypeptide parent et comprenant au moins une modification d'acide aminé dans la région Fc.

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