Optimized minigenes and peptides encoded thereby

Details Optimized minigenes and peptides encoded thereby Optimized minigenes and peptides encoded thereby

A - Human Necessities

61

K

A61K 38/00 (2006.01) A01N 43/04 (2006.01) A61K 39/21 (2006.01) A61K 39/295 (2006.01) C07K 14/115 (2006.01) C07K 14/16 (2006.01) C12N 15/86 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2394748

This present invention relates to the field of biology. In particular, it relates to polyepitopic vaccines and methods of designing such vaccines to provide increased immunogenicity. In certain embodiments, the polyepitopic vaccines is encoded by a minigene that provides optimized immunogenicity of the construct.

L'invention concerne le domaine de la biologie. Elle concerne, en particulier, des vaccins polyépitopiques et des procédés de préparation de ces vaccins afin d'obtenir une immunogénicité améliorée. Dans certains modes de réalisation, ce vaccin polyépitopique est codé par un minigène permettant d'obtenir une immunogénicité optimisée du produit génétique.

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