Optimized minizymes and miniribozymes and uses thereof

Details Optimized minizymes and miniribozymes and uses thereof Optimized minizymes and miniribozymes and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 31/70 (2006.01) C07H 21/02 (2006.01) C12N 9/22 (2006.01) C12N 15/63 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2222793

This invention is directed to improved catalytic compounds, minizymes and miniribozymes, capable of hybridizing with a target RNA to be cleaved. The minizymes and miniribozymes and compositions of the present invention may be used in vitro or in vivo. They may be used as diagnostic or therapeutic agents.

L'invention a pour objet des composés catalytiques, des minizymes et des miniribozymes, pouvant s'hybrider avec un ARN cible devant être coupé. Les minizymes et les miniribozymes ainsi que les compositions selon l'invention peuvent être utilisés in vivo ou in vitro. Par ailleurs, ils peuvent être utilisés comme agents thérapeutiques ou diagnostiques.

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