A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/55 (2006.01)
Patent
CA 2541402
Solid, pharmaceutical dosage forms of [2-(8,9-dioxo-2,6-diazabicyclo [5.2.0]non~1(7)-en-2-yl)alkyl]phosphonic acid and derivatives thereof are disclosed. In addition, methods of use are disclosed for the treatment, inter alia, of cerebral vascular disorders, anxiety disorders; mood disorders; schizophrenia; schizophreniform disorder; schizoaffective disorder; cognitive impairment; chronic neurodegenerative disorders; inflammatory diseases; fibromyalgia; complications from herpes zoster; prevention of tolerance to opiate analgesia; withdrawal symptoms from addictive drugs; and pain.
La présente invention concerne des formes posologiques pharmaceutiques solides d'acide phosphonique [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)alkyl] et de dérivés de celui-ci. En outre, l'invention concerne des méthodes d'utilisation de ces formes posologiques pharmaceutiques pour le traitement, entre autres, de troubles vasculaires cérébraux, de troubles de l'anxiété, de troubles de l'humeur, de la schizophrénie, de troubles schizophréniformes, de troubles schizo-affectifs, de troubles cognitifs, de troubles neurodégénératifs chroniques, de maladies inflammatoires, d'une fibromyalgie ; de complications suite à un zona. Ces compositions permettent également de prévenir la tolérance à une analgésie opiacée, aux symptômes de sevrage de drogues induisant une pharmacodépendance, et à la douleur.
Ashraf Muhammad
Benjamin Eric J.
Brandt Michael R.
Cloud William F.
Islam Mohammed
Torys Llp
Wyeth
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