Oral and dental hygiene preparations

Details Oral and dental hygiene preparations Oral and dental hygiene preparations

A - Human Necessities

61

K

167/319

A61K 8/41 (2006.01) A61K 8/55 (2006.01) A61Q 11/00 (2006.01)

Patent

CA 1244352

ABSTRACT OF THE DISCLOSURE Oral and dental hygiene preparations containing quaternary ammonium compounds of the formula Image (I) wherein R1 is an n-alkyl group, preferably containing from 8 to 12 carbon atoms, R2 is hydrogen, a CH3-group or a CH2OH group and R3 is a CH3-group or a group of the formula -CH2-CH(OH)-R2, A is an inorganic or organic acid anion and n is the basicity of the anion. The quaternary ammonium compounds of formula I can have a plaque inhibiting effect and show only slight antimicrobial activity. R1 is preferably an n-decyl group, R2 is hydrogen and R3 is a CH3-group or a 2-hydroxyethyl group. The oral and dental hygiene preparations also preferably contain fluorides and/or organophosphonates as the anion A.

468408

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