Oral antidepressant formulation comprising acetylsalicylic...

A - Human Necessities – 61 – K

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A61K 31/616 (2006.01) A61K 31/00 (2006.01) A61P 25/24 (2006.01)

Patent

CA 2543640

Oral antidepressant formulation comprising an effective antidepressant amount of one or more pharmaceutically acceptable antidepressant active agents advantageously selected of he group consisting of SSRIs, SNRIs (serotonin nordraline reuptake inhibitors) CRF antagonists, NK1 antagonists, NK2 antagonists, NK3 antagonists and combinations thereof, and an effective amount lower than 50mg of at least a compound selected from the group consisting of acetylsalicylic acid, derivatives of acetylsalicylic acid, and mixtures thereof, for reducing the onset of antidepressant action.

L'invention porte sur une formulation orale comprenant une quantité effective d'un ou plusieurs agents antidépresseurs acceptables d'un point de vue pharmaceutique et sélectionnés de manière avantageuse dans le groupe comprenant des SSRI, des antagonistes CRF de SNRI (inhibiteurs du recaptage de la nordraline de la sérotonine), des antagonistes NK1, des antagonistes NK2, des antagonistes NK3 et des combinaisons de ceux-ci, et une quantité effective inférieure à 50 mg d'au moins un composé sélectionné dans le groupe comprenant l'acide acétylsalicylique, des dérivés de celui-ci et des mélanges de ceux-ci, pour réduire l'action des antidépresseurs.

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