Oral care compositions comprising zinc and phytate

Details Oral care compositions comprising zinc and phytate Oral care compositions comprising zinc and phytate

A - Human Necessities

61

K

A61K 8/55 (2006.01) A61K 8/27 (2006.01) A61Q 11/00 (2006.01)

Patent

CA 2634758

Disclosed are oral care compositions and their use, comprising in an orally acceptable carrier: (a) from about 0.01 to about 10 % by weight of an essentially water-insoluble zinc compound, and (b) from about 0.01 % to about 10 % by weight of a compound having C-O-P bonds selected from polyphosphorylated inositol compounds such as phytic acid, myo-inositol pentakis(dihydrogen phosphate); myo-inositol tetrakis(dihydrogen phosphate), myo-inositol trikis(dihydrogen phosphate), and an alkali metal, alkaline earth metal or ammonium salt thereof. The compositions are effective in preventing and controlling oral cavity conditions including plaque, calculus, caries, periodontal disease, mouth malodor and dental erosion and have acceptable aesthetics without the unpleasant astringent and metallic taste associated with the use of zinc.

Cette invention se rapporte à des compositions pour soins buccaux contenant un excipient acceptable sur le plan oral, ainsi qu~à leur utilisation. Elles contiennent (a) d~environ 0,01 % à environ 10 % en poids d~un composé de zinc généralement insoluble dans l~eau, et (b) d~environ 0,01 % à environ 10 % en poids d~un composé contenant des liaisons C-O-P sélectionné parmi les composés d~inositol phosphorylés tels que l~acide phytique, le myo-inositol pentakis (phosphate de dihydrogène), le myo-inositol tétrakis (phosphate de dihydrogène), le myo-inositol trikis (phosphate de dihydrogène), et un métal alcalin, un métal alcalino-terreux ou leur sel d~ammonium. Ces compositions sont efficaces pour prévenir et contrôler les problèmes de la cavité buccale comme la plaque dentaire, le tartre, les caries, la parodontopathie, la mauvaise haleine et l~érosion dentaire. Elles sont esthétiquement acceptables et n~ont pas ce goût astringent et métallique désagréable associé à l'utilisation du zinc.

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