A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/423 (2006.01) A61K 9/08 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 47/02 (2006.01) A61K 47/18 (2006.01) A61K 47/32 (2006.01) A61P 29/00 (2006.01)
Patent
CA 2653023
An oral composition comprising 3-[5-[4- (cyclopentyloxy)-2-hydroxybenzoyl]-2-[(3-hydroxy-1,2- benzisoxazol-6-yl)methoxy]phenyl]propionic acid or a salt thereof and polyvinylpyrrolidone. The oral composition is useful as a pharmaceutical composition for oral application having the following properties (1) to (3): (1) no new-type facility is required for the production of the composition; (2) the composition can be produced by a simple process; and (3) the composition can be dissolved stably in the gastrointestinal tract even when the pH value in the gastrointestinal tract varies and therefore is improved in gastrointestinal adsorption.
L'invention concerne une composition orale comprenant de l'acide 3-[5-[4-(cyclopentyloxy)-2-hydroxybenzoyl]-2-[(3-hydroxy-1,2-benzisoxazol-6- yl)méthoxy]phényl]propionique ou un sel de celui-ci et de la polyvinylpyrrolidone. La composition orale est utile en tant que composition pharmaceutique pour une application orale ayant les propriétés (1) à (3) suivantes: (1) aucun équipement d'un nouveau type n'est requis pour la fabrication de la composition ; (2) la composition peut être obtenue par un procédé simple ; (3) la composition peut être dissoute de façon stable dans le tractus gastro-intestinal même lorsque la valeur de pH dans le tractus gastro-intestinal varie et, par conséquent, présente une adsorption gastro-intestinale améliorée.
Kakuda Sahoe
Kaneko Masashi
Yahata Tatsuhito
Marks & Clerk
Toyama Chemical Co. Ltd.
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