Oral compositions containing polyguanidinium compounds and...

A - Human Necessities – 61 – K

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A61K 6/027 (2006.01) A61K 9/00 (2006.01) A61K 31/785 (2006.01) A61Q 11/00 (2006.01)

Patent

CA 2760130

The invention describes the modification of polyamine-based materials to form polyguanidine compounds that are useful for their antimicrobial, anticaries, and muccoadhesive properties. The present invention also relates to methods for preventing or treating periodontal disease and caries which include delivering a therapeutically effective amount of an oral composition containing a polyguanidine compound into an oral cavity.

La présente invention concerne la modification de substances à base de polyamines destinées à former des composés polyguanidine qui sont utiles pour leurs propriétés antimicrobiennes, anticaries, et mucoadhésives. La présente invention concerne également des procédés destinés à prévenir ou à traiter une maladie parodontaire et des caries qui comprennent l'administration d'une quantité thérapeutique efficace d'une composition orale contenant un composé polyguanidine à l'intérieur d'une cavité orale.

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