Oral compositions of levosimendan

A - Human Necessities – 61 – K

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A61K 31/50 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2304702

A composition for oral administration comprising substantially pure crystalline polymorphic form (I) of levosimendan as an active ingredient together with a pharmaceutically acceptable carrier is described. Polymorphic form (I) of levosimendan is rapidly absorbed from the gastrointestinal tract and is useful in the treatment of congestive heart disease.

aette invention se rapporte à une composition destinée à être administrée par voie orale, qui comprend une forme (I) polymorphe cristalline essentiellement pure de levosimendan, comme principe actif, associée à un excipient acceptable sur le plan pharmaceutique. Cette forme (I) polymorphe de levosimendan est rapidement absorbée dans le tractus gastro-intestinal et elle est utile dans le traitement des maladies cardiaques congestives.

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