Oral delivery of gene constructs

Details Oral delivery of gene constructs Oral delivery of gene constructs

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 9/00 (2006.01) A61K 9/48 (2006.01) A61K 31/70 (2006.01)

Patent

CA 2221323

The present invention is a method for the delivery of a gene construct to a targeted portion in the gastrointestinal tract. Delivery of the gene construct occurs as a bolus dose that will cause the expression of a therapeutically effective amount of a therapeutic protein at the target site. The invention is also directed to a device for delivery of the gene construct at the target site.

L'invention porte sur un procédé d'administration d'un produit de recombinaison génique destiné à une région ciblée des voies digestives. Ledit produit de recombinaison se présente sous la forme d'une dose de charge en bolus qui produit l'expression d'une quantité à effet thérapeutique d'une protéine traitante dans le site cible. L'invention porte également sur le dispositif permettant d'acheminer ledit produit de recombinaison génique jusqu'à un site cible.

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