Oral delivery of peptide

Details Oral delivery of peptide Oral delivery of peptide

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 9/127 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01)

Patent

CA 2420032

Proliposome of a peptidyl drug and enteric preparations containing said proliposome are disclosed by the present invention, wherein said proliposome is prepared by dissolving the peptidyl drug and phospolipid in an organic solvent and coating the resulting solution with water-soluble chitosan. The oral delivery system of peptide using the proliposome and the enteric preparation according to the present invention remarkably increases stability and bioavailability of a peptidyl drug.

La présente invention concerne un proliposome de médicament à base de peptidyle et des préparations entériques contenant ledit proliposome. Pour obtenir ce proliposome, on dissout le médicament à base de peptidyle avec un phospholipide dans un solvant organique, puis on recouvre la solution ainsi obtenue de chitosane hydrosoluble. Ce système d'administration per os de peptide faisant intervenir le proliposome et les préparations entériques selon l'invention permet d'augmenter considérablement la stabilité et la biodisponibilité des médicaments à base de peptidyle.

Affiliated with

Also associated with

Rating

Oral delivery of peptide does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Oral delivery of peptide, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Oral delivery of peptide will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2073385