Oral dosage forms of bendamustine

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/48 (2006.01) A61K 9/14 (2006.01) A61K 31/4184 (2006.01)

Patent

CA 2745525

In the present invention there is provided an oral pharmaceutical composition, comprising bendamustine or a pharmaceutically acceptable, ester, salt or solvate thereof as an active ingredient, and a pharmaceutically acceptable excipient, which is a pharmaceutically acceptable non-ionic surfactant, selected from the group consisting of polyethoxylated castor oil or derivative thereof and a block copolymer of ethylene oxide and propylene oxide.

La présente invention concerne une composition pharmaceutique à administration par voie orale, comprenant de la bendamustine ou un ester, sel ou solvate pharmaceutiquement acceptable de ladite en tant quingrédient actif, et un excipient pharmaceutiquement acceptable, pouvant être un agent tensioactif non ionique pharmaceutiquement acceptable, sélectionné dans le groupe constitué de lhuile de ricin polyéthoxylée ou dun dérivé de ladite et dun copolymère bloc doxyde déthylène et doxyde de propylène.

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