Oral dosage forms of gemcitabine derivatives

Details Oral dosage forms of gemcitabine derivatives Oral dosage forms of gemcitabine derivatives

A - Human Necessities

61

K

A61K 31/7068 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2600399

The present invention relates to oral dosage forms of certain long chain saturated and monounsaturated fatty acid derivatives of 2',2'- difluorodeoxycytidine (Gemcitabine). In particular, the present invention relates to the use of the said gemcitabine derivatives or a pharmaceutical acceptable salt thereof for preparing an oral dosage form ameliorating compliance in treatment of cancer.

L'invention concerne des formes de dosage oral de certains dérivés d'acides gras saturés et mono-insaturés à chaîne longue de 2',2'-difluorodéoxycytidine (Gemcitabine). L'invention concerne, en particulier, l'utilisation de dérivés de gemcitabine ou d'un sel pharmaceutiquement acceptable de ceux-ci pour préparer une forme de dosage oral permettant d'améliorer l'adhésion au traitement d'un cancer.

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