A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/70 (2006.01) A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01) A61K 9/48 (2006.01) A61K 9/02 (2006.01)
Patent
CA 2344306
A drug delivery system for enhancing the bioavailability of glycyrrhetin having been orally administered. This drug delivery system is one aiming at delivering oral drugs to the large intestine which comprises glycyrrhetin in an amount sufficient for selectively releasing glycyrrhetin in the large intestine at a high concentration exceeding the speed of the hydrolysis of glycyrrhetin by the intestinal flora and pharmaceutically acceptable carrier(s). It is preferable that the carriers partly or totally comprise sorbefacient(s) selected from the group consisting of pharmaceutically acceptable organic acids, surfactants and chelating agents.
Système d'administration de médicament permettant d'améliorer la biodisponibilité de la glycyrrhétine administrée par voie orale. Ce système d'administration, qui a pour but de délivrer dans le colon des médicaments administrés par voie orale, comprend de la glycyrrhétine, en une quantité suffisante pour permettre sa libération sélective dans le colon à une concentration dépassant la vitesse de son hydrolyse par la flore intestinale, et un ou plusieurs excipients pharmaceutiquement acceptables. De préférence, les excipients comprennent un ou plusieurs agents favorisant l'absorption, choisis dans le groupe comprenant les acides organiques, les tensioactifs et les agents chélatants pharmaceutiquement acceptables.
Amato Pharmaceutical Products Ltd.
Ridout & Maybee Llp
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