Oral extended release tablets and methods of making and...

Details Oral extended release tablets and methods of making and... Oral extended release tablets and methods of making and...

A - Human Necessities

61

K

A61K 9/28 (2006.01) A61K 9/00 (2006.01) A61K 31/00 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2501324

The present invention is directed to oral dosage forms for extended release, including a dosage form for pH independent extended release, of at least one drug to a subject. The present invention is also directed to methods of making and using the dosage forms to treat or prevent a subject for various conditions. Specific extended release formulations of crystalline clindamycin free base are also provided. The crystalline clindamycin free base oral formulations of the present invention provide a means for treating or preventing gram-positive bacterial infections with a minimal number of treatments per day, potentially, as little as once or twice per day.

L'invention concerne une forme posologique orale pour une libération étendue, comprenant une forme posologique pour une libération étendue, indépendante du pH, d'au moins un médicament à un sujet. L'invention concerne également des procédés de fabrication et d'utilisation de la forme posologique pour traiter ou prévenir de nombreux états pathologiques chez un sujet. L'invention concerne des formulations à libération étendue spécifiques de base libre de clindamycine cristalline. Les formulations orales à base libre de clindamycine cristalline de l'invention offrent un moyen de traitement ou de prévention des infections bactériennes gram positif au moyen d'un nombre minimum de traitements par jour, une fois ou deux fois par jour.

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