Oral liquid formulations of benzoxazinones hiv reverse...

A - Human Necessities – 61 – K

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Details

A61K 31/536 (2006.01) A61K 9/48 (2006.01) A61K 47/14 (2006.01) A61P 31/18 (2006.01)

Patent

CA 2319609

A palatable oral liquid pharmaceutical composition of benzoxazinone compounds useful as HIV reverse transcriptase inhibitors comprising the benzoxazinone active ingredient in a liquid vehicle comprising medium chain fatty acid triglycerides. Other formulating agents such as sweetening agents, lecithin suspending agents, etc. may be optionally added.

La présente invention concerne une composition pharmaceutique orale liquide de goût agréable renfermant des composés de benzoxazinone, utilisés comme inhibiteurs de transcriptase inverse de VIH, renfermant le principe actif à base de benzoxazinone contenu dans un excipient liquide comportant des triglycérides à chaînes moyennes. On peut éventuellement ajouter d'autres agents de formulation tels que les édulcorants, les agents de fixation à base de lécithine, etc.

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