Oral liquid formulations of benzoxazinones hiv reverse...

Details Oral liquid formulations of benzoxazinones hiv reverse... Oral liquid formulations of benzoxazinones hiv reverse...

A - Human Necessities

61

K

A61K 31/535 (2006.01) A61K 9/00 (2006.01) A61K 9/48 (2006.01) A61K 31/536 (2006.01) A61K 47/44 (2006.01)

Patent

CA 2319740

A palatable oral liquid pharmaceutical composition of benzoxazinone compounds useful as HIV reverse transcriptase inhibitors comprising the benzoxazinone active ingredient in a liquid vehicle comprising a vegetable oil selected from olive oil, peanut oil, soybean oil, corn oil, safflower oil, sunflower oil, canola oil or walnut oil. Other formulating agents such as sweetening agents, lecithin suspending agents, etc. may be optionally added.

La présente invention concerne une composition pharmaceutique orale liquide de goût agréable, renfermant des composés de benzoxazinone utilisés comme inhibiteurs de transcriptase inverse de VIH, renfermant le principe actif à base de benzoxazinone contenu dans un excipient liquide comportant une huile végétale sélectionnée à partir d'huile d'olive, d'huile d'arachide, d'huile de soja, d'huile de maïs, d'huile de carthame, d'huile de tournesol, d'huile de colza ou d'huile de noix. On peut éventuellement ajouter d'autres agents de formulation tels que les édulcorants, les agents de fixation à base de lécithine, etc.

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