A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/20 (2006.01) A61K 35/60 (2006.01) A61K 38/23 (2006.01) A61K 47/18 (2006.01) A61K 47/34 (2006.01) A61K 47/38 (2006.01) A61P 19/08 (2006.01) A61P 19/10 (2006.01)
Patent
CA 2436599
Solid pharmaceutical compositions suitable for the oral delivery of pharmacologically active agents, e.g. peptides, comprising a therapeutically- effective amount of a pharmacologically active agent; a crospovidone or povidone; and a delivery agent for said pharmacologically active agent are disclosed. The compositions provide excellent oral bioavailability of pharmacologically active agents, particularly calcitonin.
L'invention concerne des compositions pharmaceutiques solides utilisées dans l'administration orale de principes actifs sur le plan pharmacologique, par exemple des peptides. Ces compositions contiennent une quantité efficace sur le plan thérapeutique d'un principe actif sur le plan pharmacologique, une crospovidone ou une povidone, et un agent d'administration du principe actif sur le plan pharmacologique. Ces compositions présentent une excellente biodisponibilité orale des principes actifs sur le plan pharmacologique, notamment de la calcitonine.
Ault Joseph M.
Azria Moise
Bateman Simon David
Fai-Ying Yang Rebecca
Sikora Joseph
Fetherstonhaugh & Co.
Novartis Ag
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