A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/40 (2006.01) A61K 9/00 (2006.01)
Patent
CA 2429650
The application discloses oral pharmaceutical compositions which are tasted in the mouth during administration. Fast-dissolving tablets, chewable tablets and effervescent dispersions are exemplified. To mask the taste of unpleasant- tasting active ingredients, it has been found that blending with cyclodextrin without the conventional complex formation is effective. Consequently more economical modes of manufacture such as simple granulation and dry blending can be used.
L'invention concerne des compositions pharmaceutiques orales qui sont goûtées dans la bouche durant leur administration. On donne en exemple des cachets à dissolution rapide, à croquer, et des dispersions effervescentes. Afin de masquer le goût de principes actifs déplaisants, on a trouvé que le mélange avec une cyclodextrine, sans formation de complexe conventionnel, est efficace. En conséquence, il est possible d'utiliser des modes économiques de fabrication tels qu'une simple granulation et un mélange à sec.
Bellorini Lorenzo
Ciccarello Franco
Milani Rita
Stroppolo Federico
Alpex Pharma Sa
Elan Corporation Plc
Kirby Eades Gale Baker
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