A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/164
A61K 9/32 (2006.01) A61K 9/50 (2006.01)
Patent
CA 2000932
The invention relates to an oral pharmaceutical multiple units formulation comprising individual cores containing a pharmacologically active substance, said cores being provided with a coating consisting essentially of a polymer, that is insoluble in, impermeable to and non-soluble in water and in gastrointestinal fluids, and a watersoluble pore-creating substance, which is randomly distributed in said polymer, whereby said coated cores form units providing an essential zero order diffusion controlled release rate of said active substance. The invention also comprises a method of preparing these formulations.
Hermansson Christer
Kulstad Soren
Malmqvist-Granlund Karin
Gacell Laboratories Ab
Gowling Lafleur Henderson Llp
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