Oral pharmaceutical dosage forms comprising a proton pump...

Details Oral pharmaceutical dosage forms comprising a proton pump... Oral pharmaceutical dosage forms comprising a proton pump...

A - Human Necessities

61

K

A61K 31/4439 (2006.01) A61K 9/20 (2006.01) A61K 9/26 (2006.01) A61K 31/445 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2214033

An oral pharmaceutical dosage form comprising a proton pump inhibitor and one or more prokinetic agents in a fixed formulation, wherein the proton pump inhibitor is protected by an enteric coating layer. The fixed formulation is in the form of multilayered tablets, capsules or multiple unit tableted dosage forms. The multiple unit dosage fortes are most preferred. The new fixed formulation is especially useful in the treatment of disorders associated with gastro oesophageal reflux diseases.

Forme galénique par voie orale comprenant un inhibiteur de la pompe à protons et un ou plusieurs agent pro-cinétiques dans une formulation fixe, l'inhibiteur de la pompe à protons étant protégé par une couche de revêtement gastro-résistant. La formulation fixe se présente sous la forme de capsules, de comprimés à plusieurs couches ou de formes galéniques en comprimés à unités multiples. Les formes galéniques à unités multiples sont idéales. La nouvelle formulation fixe est particulièrement utile dans le traitement de troubles associés aux affections se manifestant par un reflux gastro-oesophagien.

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